Baltic Imaging Center » Projects » Cerebral Representation of Occlusion

Projects

Cerebral Representation of Occlusion

Bernd Kordaß, Rita Lickteig, Elisa Schenkenberger, Janina Dammann, Marius Ernst and Martin Lotze

We are interested in the cerebral representation of occlusal movements in the temporomandibular joint and its pathology. We are therefore conducting basic research on TMJ-movement representation in the brain and its alteration in TMJ-disorders. In addition, we are interested in therapy approaches for successfully treating chronic pain in TMJ-disorders.

Our research on TMJ-pain had been funded from 2017 to 2021 by the German Research foundation (DFG)
Grey matter volume changes in clinical samples with temporomandibular disorder:

Recent Literature:
Klepzig K., Wendt J., Teusch L., Rickert C., Kordaß B., Lotze M. (2024) Pain, stress and anxiety in temperomandibular disorders were affected by maxillar splints. Journal of Oral Rehabilitation, doi: 10.1111/joor.13678.
Domin M.*, Grimm N.*, Klepzig K., Schmidt C.O., Kordass B., Lotze M. (2021) Grey matter brain alterations in temporomandibular disorder tested in a population cohort and three clinical samples, Journal of Pain, in press.
Dammann J., Klepzig K., Schenkenberger E., Kordass B., Lotze M. (2019) Association of decrease in anterior insula fMRI activation with changes in trait anxiety in patients with craniomandibular disorder (CMD), Behavioral Brain Research, in press.
Ernst M., Schenkenberger A. E., Domin M., Kordass B., Lotze M. (2019) Effects of centric mandibular splint therapy on orofacial pain and cerebral activation patterns – a pilot study. Clin Oral Invest., in press.
link: link.springer.com/content/pdf/10.1007%2Fs00784-019-03064-y.pdf
Lickteig R.*, Lotze M.*, Kordass B. (2013) Successful therapy for temporomandibular pain alters anterior insula and cerebellar representations of occlusion. Cephalagia, 33(15):1248-57. * equal contribution
Lickteig R., Lotze M., Lucas C., Domin M., Kordass B. (2011) Changes in cortical activation in craniomandibular disorders during splint therapy – a single subject fMRI study. Annals of Anatomy, 194(2):212-5.

Literature on healthy participants:
Lotze M, Domin M, Lucas C, Kordass B (2011) The cerebral representation of temporomandibular joint occlusion and its alternation by occasional occlusal splints; Human Brain Mapping, 33(12):2984-93.
Mihai PG., von Bohlen und Halbach O., Lotze M. (2013) Differentiation of cerebral representation of occlusion and swallowing with fMRI. Am J Physiol.304(10):G847-54.
Lotze M., Domin M., Kordass B. (2017) Symmetry of fMRI activation in the primary sensorimotor Cortex during unilateral chewing. Clinical Oral Investigations, 21(4):967-973.